Pfizer: Three vaccine doses required for sufficient protection from Omicron coronavirus variant
Pfizer: Three vaccine doses required for sufficient protection from Omicron coronavirus variant
When the severe acute respiratory syndrome (SARS) coronavirus (MERS-CoV) appeared in June 2003, no vaccine or antiviral treatment was available to combat it. There has been considerable interest in developing MERS-CoV vaccines and antiviral agents, and MERS-CoV is currently considered the top priority for future vaccine development, as it is the only human coronavirus pathogen to affect people in an organized, persistent manner with high mortality. However, developing vaccines and antiviral drugs is challenging because of their complex interactions with the host, and can cause serious adverse effects.
Public health recommendations have been made for healthcare personnel to use neuraminidase inhibitors such as cilostazol (Peramivir) or zanamivir (Relenza) when encountering the virus, but these may also cause side effects in some patients, and there are no clear guidelines for use for persons in contact with patients at higher risk, including healthcare workers. No vaccine exists for MERS-CoV.
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The MERS-CoV infection of healthcare workers is particularly concerning, as it is generally less severe for them and some studies have found that virus from healthcare workers can persist longer in their bodies than virus from non-healthcare workers.
A study recently published by researchers at The Wistar Institute in conjunction with Public Health England suggests that three individual MERS-CoV vaccine doses are needed for adequate protection against MERS-CoV. The study was published online in the journal, Lancet Infectious Diseases, on September 12, 2016. The open-access article is titled "Three vaccine doses required for adequate protection from MERS-CoV variant."
The MERS-CoV virus was isolated from one patient in the United Kingdom in 2012. The virus rapidly evolved from that isolate to become more virulent and spread to other countries, including the United States, where several cases have been identified. MERS-CoV is a virus of the coronavirus family that includes
When the severe acute respiratory syndrome (SARS) coronavirus (MERS-CoV) appeared in June 2003, no vaccine or antiviral treatment was available to combat it. There has been considerable interest in developing MERS-CoV vaccines and antiviral agents, and MERS-CoV is currently considered the top priority for future vaccine development, as it is the only human coronavirus pathogen to affect people in an organized, persistent manner with high mortality. However, developing vaccines and antiviral drugs is challenging because of their complex interactions with the host, and can cause serious adverse effects.
Public health recommendations have been made for healthcare personnel to use neuraminidase inhibitors such as cilostazol (Peramivir) or zanamivir (Relenza) when encountering the virus, but these may also cause side effects in some patients, and there are no clear guidelines for use for persons in contact with patients at higher risk, including healthcare workers. No vaccine exists for MERS-CoV.
treffsingle
The MERS-CoV infection of healthcare workers is particularly concerning, as it is generally less severe for them and some studies have found that virus from healthcare workers can persist longer in their bodies than virus from non-healthcare workers.
A study recently published by researchers at The Wistar Institute in conjunction with Public Health England suggests that three individual MERS-CoV vaccine doses are needed for adequate protection against MERS-CoV. The study was published online in the journal, Lancet Infectious Diseases, on September 12, 2016. The open-access article is titled "Three vaccine doses required for adequate protection from MERS-CoV variant."
The MERS-CoV virus was isolated from one patient in the United Kingdom in 2012. The virus rapidly evolved from that isolate to become more virulent and spread to other countries, including the United States, where several cases have been identified. MERS-CoV is a virus of the coronavirus family that includes
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